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進行・再発大腸癌の分子標的治療
主な内容
1 進行・再発大腸癌薬物治療の進め方
Pin Point
2 大腸癌薬物治療に用いられる分子標的治療薬
1)ベバシズマブ
2)ラムシルマブ
3)アフリベルセプト ベータ
4)セツキシマブ
5)パニツムマブ
6)レゴラフェニブ
Pin Point
3 個別化治療と薬剤―バイオマーカーを用いた治療法の選択
Pin Point
4 臨床現場における分子標的治療薬の選び方
1)ベースレジメンの決定と,分子標的治療薬の選択はこう行う
2)RAS 野生型症例への一次治療に用いる分子標的治療薬はこう選ぶ
―血管新生阻害薬か?抗EGFR 抗体薬か?
3)二次治療以降の分子標的治療薬,これが選択のコツ
4)有害事象を抑えながら,治療を完遂させるためのポイントはこれ
Pin Point
5 分子標的治療に伴う有害事象とその対応の原則
1)骨髄機能抑制(赤血球減少,血小板減少を中心に)
2)発熱性好中球減少症
3)全身倦怠感
4)悪心・嘔吐
5)下痢・便秘
6)口内炎
7)肝障害
8)腎障害
9)神経症状
10)脱毛
11)出血
12)皮膚症状(ざ瘡様皮疹)
13)手足皮膚反応
14)インフュージョンリアクション
Pin Point
2017年9月12日
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