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知っておきたい クロストリディオイデス・ディフィシル感染対策Point20
※BASE株式会社の決済システムを使用しています。
主な内容
クロストリディオイデス・ディフィシル物語
Point 1 『芽胞形成菌』という、非常に守りの堅い特別な細菌です。
Point 2 腸の中で増えて、危険な『外毒素(トキシン)』を作り出します。
Point 3 熱にも乾燥にも耐えられて、環境に長く生きられます。
Point 4 消毒薬が効きにくいので、消毒の際には工夫が必要です。
Point 5 細菌なのに、抗菌薬を使うとむしろ出てきてしまいます。
Point 6 病院内の患者にこっそりと潜み、広がり、悪さをします。
Point 7 症状は単純ですが、意外と見逃しやすいです。
Point 8 重症化することがあり、あなどれません。
Point 9 治ったように見えても、何度も繰り返し発症します。
Point10 検査は必要なときにだけ行い、結果には慎重な判断が必要です。
Point11 手袋は絶対に必要ですが、手袋だけでは伝播を防げません。
Point12 個人防護具は、着脱だけでなく、廃棄まで気を抜けません。
Point13 伝播を防ぐためには、発症者をしっかりと管理することが重要です。
Point14 伝播リスクの高い場所を踏まえた清掃が、環境からの伝播を防ぎます。
Point15 環境表面の清掃にアルコール消毒薬は使用できません。
Point16 主に病院内で感染しますが、市中で感染することもあります。
Point17 患者・家族の協力なしには伝播は防げません。
Point18 『抗菌薬適正使用支援』という考え方が予防の要です。
Point19 集団発生することがあり、日常的に監視をする必要があります。
Point20 強毒タイプがいるので、その動向には注意が必要です。
2018年1月15日
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進行・再発大腸癌の分子標的治療
主な内容
1 進行・再発大腸癌薬物治療の進め方
Pin Point
2 大腸癌薬物治療に用いられる分子標的治療薬
1)ベバシズマブ
2)ラムシルマブ
3)アフリベルセプト ベータ
4)セツキシマブ
5)パニツムマブ
6)レゴラフェニブ
Pin Point
3 個別化治療と薬剤―バイオマーカーを用いた治療法の選択
Pin Point
4 臨床現場における分子標的治療薬の選び方
1)ベースレジメンの決定と,分子標的治療薬の選択はこう行う
2)RAS 野生型症例への一次治療に用いる分子標的治療薬はこう選ぶ
―血管新生阻害薬か?抗EGFR 抗体薬か?
3)二次治療以降の分子標的治療薬,これが選択のコツ
4)有害事象を抑えながら,治療を完遂させるためのポイントはこれ
Pin Point
5 分子標的治療に伴う有害事象とその対応の原則
1)骨髄機能抑制(赤血球減少,血小板減少を中心に)
2)発熱性好中球減少症
3)全身倦怠感
4)悪心・嘔吐
5)下痢・便秘
6)口内炎
7)肝障害
8)腎障害
9)神経症状
10)脱毛
11)出血
12)皮膚症状(ざ瘡様皮疹)
13)手足皮膚反応
14)インフュージョンリアクション
Pin Point